Iyer, Malliga R’s team published research in ACS Omega in 2022-09-06 | 94-20-2

ACS Omega published new progress about One-pot synthesis. 94-20-2 belongs to class amides-buliding-blocks, and the molecular formula is C10H13ClN2O3S, Category: amides-buliding-blocks.

Iyer, Malliga R.; Bhattacharjee, Pinaki; Kundu, Biswajit; Rutland, Nicholas; Wood, Casey M. published the artcile< One-Pot Synthesis of Thio-Augmented Sulfonylureas via a Modified Bunte's Reaction>, Category: amides-buliding-blocks, the main research area is thio sulfonylurea preparation; sulfonylurea one pot Bunte reaction.

Authors report the development of a one-pot Bunte’s reaction-enabled expeditious platform under aqueous conditions for the scalable conversion of sulfonylureas to synthetically versatile thio-sulfonylureas. The reaction was further propagated in the same pot to yield diverse chiral and achiral isothiosulfonyl analogs. The protocol enabled the synthesis of various drug-like mols. and was applied to an enantiomeric synthesis of a cannabinoid receptor antagonist SLV326.

ACS Omega published new progress about One-pot synthesis. 94-20-2 belongs to class amides-buliding-blocks, and the molecular formula is C10H13ClN2O3S, Category: amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics