Bisset, Alexander A.; Dishington, Allan; Jones, Teyrnon; Clarkson, Guy J.; Wills, Martin published the artcile< Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines>, Electric Literature of 1192620-83-9, the main research area is pyridine pyridinone preparation.
The synthesis of a series of pyridones, from their 2-hydroxypyridine or 2-methoxypyridine precursors, is described, along with studies into their reductions to saturated heterocycles. A number of 5-acyl-pyridones were prepared and were evaluated as substrates for asym. transfer hydrogenation prior to conversion to saturated heterocycles. The enantioselective reduction of 5-acetyl-1-benzyl-2,4(1H,3H)-pyrimidinedione is also described. The synthesis of the target compounds was achieved using [(R)-BINAP]ruthenium diacetate, [N-[(1R,2R)-1,2-diphenyl-2-[[3-(η6-phenyl)propyl](3-phenylpropyl)amino-κN]ethyl]-4-methylbenzenesulfonamidato-κN](chloro)ruthenium [N-[(1R,2R)-2-(amino-κN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-κN]chloro[(1,2,3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]ruthenium and [N-[(1S,2S)-1,2-diphenyl-2-[[3-(η6-phenyl)propyl](3-phenylpropyl)amino-κN]ethyl]-4-methylbenzenesulfonamidato-κN](chloro)ruthenium as catalysts. The title compounds thus formed included chiral 5-(1-hydroxyethyl)-2-piperidinone derivatives
Tetrahedron published new progress about Enantioselective synthesis. 1192620-83-9 belongs to class amides-buliding-blocks, and the molecular formula is C30H31ClN2O2RuS, Electric Literature of 1192620-83-9.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics