Andres, J. Ignacio; Alonso, Jose M.; Fernandez, Javier; Iturrino, Laura; Martinez, Pedro; Meert, Theo F.; Sipido, Victor K. published their research in Bioorganic & Medicinal Chemistry Letters on December 16 ,2002. The article was titled 《2-(Dimethylaminomethyl)-tetrahydroisoxazolopyridobenzazepine derivatives. Synthesis of a new 5-HT2C antagonist with potential anxiolytic properties》.Application of 70298-88-3 The article contains the following contents:
The synthesis of 2-(dimethylaminomethyl)-2,3,3a,8-tetrahydroisoxazolo[3,2-a]pyrido[3,4-c]-[2]benzazepine and 2-(dimethylaminomethyl)-2,3,3a,8-tetrahydroisoxazolo[3,2-a]pyrido[3,2-c]-[2]benzazepine via a new route is reported. The affinities for several receptors as well as the m-chlorophenylpiperazine antagonistic activity of the compounds synthesized are described. After reading the article, we found that the author used 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3Application of 70298-88-3)
2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)―, RS(O)2―, and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOOR′); the products are amides of the corresponding acids.Application of 70298-88-3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics