《Copper-catalyzed tandem cis-carbometalation/cyclization of imine-ynamides with arylboronic acids》 was written by Wang, Hao-Ran; Huang, En-He; Luo, Chen; Luo, Wen-Feng; Xu, Yin; Qian, Peng-Cheng; Zhou, Jin-Mei; Ye, Long-Wu. Related Products of 70-55-3 And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:
Indoles I (Ar1, Ar2 = Ph, substituted Ph; X = H, OMe, Me, Br) were prepared by copper(I) acetate-catalyzed tandem carboboration-cyclization of imino-ynamides 2-tBuN:CHC6H4N(PG)CCAr1 (PG = arenesulfonyl) with areneboronic acids Ar2B(OH)2. An efficient copper-catalyzed tandem regioselective cis-carbometalation/cyclization of imine-ynamides with arylboronic acids has been developed. This method leads to a facile and practical synthesis of valuable 2,3-disubstituted indolines in moderate to excellent yields and features a broad substrate scope and wide functional group tolerance. Other significant features of this protocol include the use of readily available starting materials, high flexibility, simple procedure and mild reaction conditions. The results came from multiple reactions, including the reaction of 4-Methylbenzenesulfonamide(cas: 70-55-3Related Products of 70-55-3)
4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Related Products of 70-55-3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics