Stanetty, Peter; Krumpak, Barbara; Emerschitz, Thomas; Mereiter, Kurt published the artcile< Synthesis of benzo[d]-1,2-thiazole-1,1-dioxide derivatives via directed lithiation of 2,2-dimethyl-N-(phenylsulfonyl)-propanamides>, COA of Formula: C6H6FNO2S, the main research area is benzothiazole dioxide preparation; dimethylphenylsulfonylpropanamide lithiation cyclization electrophilic addition.
A novel synthesis of 7-substituted benz[d]-1,2-thiazole-1,1-dioxides I (R = H, CHO, CONHCMe3, CO2H, Me, OH, X = H, F, Cl) is presented including directed lithiation of 2,2-dimethyl-N-(phenylsulfonyl)-propanamides 3-XC6H4SO2NHCOCMe3, aryne-mediated cyclization and subsequent quenching of aryllithium intermediates with various electrophiles. A proposed mechanism is rationalized by some control experiments
Tetrahedron published new progress about 1524-40-9. 1524-40-9 belongs to class amides-buliding-blocks, and the molecular formula is C6H6FNO2S, COA of Formula: C6H6FNO2S.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics