Kamlar, Martin; Reiberger, Robert; Nigrini, Martin; Cisarova, Ivana; Vesely, Jan published the artcile< Enantioselective PCCP Bronsted acid-catalyzed aminalization of aldehydes>, Synthetic Route of 112253-70-0, the main research area is dihydroquinazolinone preparation enantioselective; aldehyde anthranilamide aminalization pentacarboxycyclopentadiene Bronsted acid catalyst; Brønsted acid; PCCP; aminalization; organocatalysis; pentacarboxycyclopentadiene.
Here an enantioselective aminalization of aldehydes catalyzed by Bronsted acids based on pentacarboxycyclopentadienes (PCCPs) is presented. The cyclization reaction using readily available anthranilamides as building blocks provides access to valuable 2,3-dihydroquinazolinones containing one stereogenic carbon center with good enantioselectivity (ee up to 80%) and excellent yields (up to 97%).
Beilstein Journal of Organic Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 112253-70-0 belongs to class amides-buliding-blocks, and the molecular formula is C7H7BrN2O, Synthetic Route of 112253-70-0.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics