Some scientific research about 614-76-6

Statistics shows that 2-BroMoacetanilide is playing an increasingly important role. we look forward to future research findings about 614-76-6.

Reference of 614-76-6, These common heterocyclic compound, 614-76-6, name is 2-BroMoacetanilide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

A mixture of aa (2.0 g, 9.34 mmol), tributylvinyl stannane (3.55 mL, 12.15 mmol) and Pd(PPh3)2Cl2 (1.64 g, 2.335 mmol) in toluene was heated at 95 C. under nitrogen after degassing. After 1 hour, the reaction mixture was concentrated and purified by flash chromatography (SiO2, 100% CH2Cl2 to 50% EtOAc/CH2CL2) followed by recrystalization from EtOH/H2O to give bb (732 mg, 49%). HPLC Rt=1.45 min.

Statistics shows that 2-BroMoacetanilide is playing an increasingly important role. we look forward to future research findings about 614-76-6.

Reference:
Patent; Gavai, Ashvinikumar V.; Norris, Derek J.; Han, Wen-Ching; Vite, Gregory D.; Fink, Brian E.; Tokarski, John S.; US2005/192310; (2005); A1;,
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