Reference of 154350-29-5, The chemical industry reduces the impact on the environment during synthesis 154350-29-5, name is Cyclopropanesulfonamide, I believe this compound will play a more active role in future production and life.
To a solution of cyclopropanesulfonamide (6 g, 50 mmol) in DCM (50 ml) were added triethylamine (7.5 ml, 74 mmol) followed by DMAP (0.3 g, 7.5 mmol) and di-tert-butyl dicarbonate (13 g, 59 ml) and the reaction was left stirring overnight. The solvent was removed; water, 2N HCl (40 ml) and ethyl acetate were added. The organic layer was washed with brine, dried over magnesium sulfate and evaporated to give Boc-cyclopropanesulfonamide as a white solid, used on the next step without further purification. Yield 9.73 g (88percent).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Cyclopropanesulfonamide, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; INTERMUNE, INC.; US2011/82182; (2011); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics