Application of 4943-86-6, These common heterocyclic compound, 4943-86-6, name is 2-Amino-N-(4-chlorophenyl)benzamide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A solution of the substituted benzamide (1equiv) and ortho-bromobenzaldehyde(1.41 mmol, 1 equiv) in acetonitrile (5mL) was treated with cyanuric chloride(0.022 mmol, 10 mole %). The reaction mixture was stirred at room temperature for 5-10 min and formed precipitate was filtered and recrystallised with ethanol to obtain the compounds 1, 6a, 6b and 16.
Statistics shows that 2-Amino-N-(4-chlorophenyl)benzamide is playing an increasingly important role. we look forward to future research findings about 4943-86-6.
Reference:
Article; Sharma, Moni; Mahar, Rohit; Shukla, Sanjeev K.; Kant, Ruchir; Chauhan, Prem M.S.; Tetrahedron Letters; vol. 54; 46; (2013); p. 6171 – 6177;,
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