Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 70-55-3, name is 4-Methylbenzenesulfonamide, A new synthetic method of this compound is introduced below., Application In Synthesis of 4-Methylbenzenesulfonamide
Example 3 p-Aminosulfonyl-benzoic Acid To the solution of 17.1 g (0.1 mol) of p-toluenesulfonamide prepared in Example 1, 20 g (0.5 mol) of sodium hydroxide in 300 ml of water was added in portions 20 g (0.13 mol) of potassium permanganate. The temperature raised to 70 C. spontaneously, keep the reaction mixture in 90 C. for 2 h. The mixture was then cooled and filtered, and the filtrate was acidified with HCl. The resulting precipitate was filtered, and washed with water, dried in vacuo to give the title compound (18.1 g) as white powder, yield 90%, m.p. 291-292 C.
The synthetic route of 70-55-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guo, Zongru; Cheng, Guifang; Chu, Fengming; US2004/58977; (2004); A1;,
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