Sources of common compounds: 96-30-0

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 96-30-0.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 96-30-0, name is 2-Chloro-N-methylacetamide, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 96-30-0

Step B 2-[[2-(3-Benzyloxy-phenyl)-ethyl]-(cyclopropylmethyl)amino]-N-methyl-acetamide hydrochloride; A mixture of 0.24 g (0.85 mmol) of [2-(3-benzyloxy-phenyl)-ethyl]- (cyclopropylmethyl)amine, 0.14 ml (1.00 mmol) of triethylamine, 0.11 g (1.02 mmol) of 2- chloro-N-methyl-acetamide in 3 ml of dimethylformamide was heated with microwaves to 120 0C for 2 hours. The solvent was removed and the crude residue was purified by flash chromatography (dichloromethane/methanol/Ntb 100:0:0 -? 95:5:0.5 gradient). The product obtained was dissolved in anhydrous hydrochloric acid in ethyl acetate, the solvent was removed under vacuum and the residue was triturated with diethyl ether. 0.24 g (80% yield) of the title compound was isolated as a yellow solid.1H-NMR CDCl3: 7.47-6.68 (m, 9H); 5.06 (s, 2H); 3.15 (s, 2H); 2.86-2.62 (m, 4H); 2.56 (d, 3H); 2.43 (d, 2H); 0.92 -0.67 (m, IH); 0.59 -0.44 (m, 2H); 0.16 -0.04 (m, 2H) LC-MS: MH+ = 353

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 96-30-0.

Reference:
Patent; NEWRON PHARMACEUTICALS S.P.A.; WO2007/71311; (2007); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics