Adding a certain compound to certain chemical reactions, such as: 25625-57-4, name is 2-Bromo-N-(3-(trifluoromethyl)phenyl)acetamide, belongs to amides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 25625-57-4, SDS of cas: 25625-57-4
General procedure: Urea linked alkynes 2(a-c) (1.0 mmol), 2-bromo-N-phenylacetamides3(a-f) (1.0 mmol) were dissolved in dimethylformamide(4 mL) in a round bottom flask. Sodium azide (3.0 mmol) in water (2 mL) copper sulphate (0.02 mmol) in water (2 mL) wereadded to the reaction mixture followed by addition of sodiumascorbate (0.02 mmol) and the mixture was stirred at 40 C for2e3 h. After completion of the reaction, reaction mixture wasfiltered and the solid obtained was washed with ice cold water andsmall amount of ethyl acetate to yield triazole hybrids 4(a-r).
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Reference:
Article; Kumar, Anil; Kumar, Ashwani; Lal, Kashmiri; Poonia, Nisha; Rani, Poonam; Journal of Molecular Structure; vol. 1215; (2020);,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics