In an article, author is Zhou, Christal, once mentioned the application of 2419-56-9, Name is H-Glu(OtBu)-OH, molecular formula is C9H17NO4, molecular weight is 203.2356, MDL number is MFCD00038580, category is amides-buliding-blocks. Now introduce a scientific discovery about this category, Recommanded Product: 2419-56-9.
Synthesis and characterization of thermo-sensitive block copolymer of N-isopropyl acryl amide-b-Alanine [(NIPAM)-b-(Alanine)] thin film and its doping with (AuNPs)-(SiO2NPs), (gold and silica nanoparticles) were reported. Further, composite effect on K562 (leukemia) cells was examined based on in vitro cell-based studies. The synthesis of SiO2NPs was followed through facile Stober’s sol-gel synthesis methods. The individual morphology of [(NIPAM)-b( Alanine)] thin film, AuNPs and SiO2NPs including [(NIPAM)-b-(Alanine)]@(Au)-(SiO2NPs) composite was confirmed by using TEM instrumentation. [(NIPAM)-b-(Alanine)] thin film was embedded with gold and silica nanoparticles followed by the sonication. The average size of AuNPs is 16 nm and for SiO2NPs, it is 368 nm (in diameter). Synthesized composite [(NIPAM)-b-(Alanine)]@(Au)@(SiO2NPs) is biocompatible for mankind use. However, composite used to examine the inhibitory activity on K562 cells and it shows 78% inhibition, which is significant value for 24 h treatment under humidified atmospheric conditions.
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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics