Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 6000-44-8, Name is Sodium 2-aminoacetate, molecular formula is , belongs to amides-buliding-blocks compound. In a document, author is Aziz, Hamid, Quality Control of Sodium 2-aminoacetate.
A family of calix[4]arenes with variation in steric crowding at the upper rim and incorporating pyridine and amide moieties at two of the four OH groups located in the lower rim have been synthesized and their performance as sensors for metal ions has been investigated. Two of the compounds exhibited selective interaction with Cu2+ ions with sharp colour change, observed by the naked eye. Spectroscopic and computational studies revealed that two of the compounds form 1 : 2 complexes, in which one of the Cu2+ ions interacts strongly with the phenolic OH, resulting in a colour change due to strong absorption (ICT) in the visible region. For the third compound, the Cu2+ ions coordinate with the pyridine and amide nitrogen atoms, and the Cu2+ ion could not enter inside to interact with the OH group due to restricted flexibility at the lower rim because of the bulky groups at the upper rim. The Cu2+ complexes thus formed have been used for sensing of amino acids and interestingly, one of the complexes exhibits interactions selectively with cysteine out of eighteen amino acids tested with a sharp colour change in aqueous media. The formation of the Cu2+-cysteine complex is confirmed from mass data, and the surface morphology of the complex before and after the addition of cysteine is investigated by SEM study.
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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics