A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 2419-56-9, Name is H-Glu(OtBu)-OH, molecular formula is C9H17NO4. In an article, author is Kastner, H.,once mentioned of 2419-56-9, Application In Synthesis of H-Glu(OtBu)-OH.
Total synthesis of the proposed structure of baulamycin A was performed. The spectral properties of the synthetic compound differ from those reported for the natural product. On the basis of comprehensive NMR. study; we proposed two other possible structures for natural baulamycin A. Total syntheses of these two substances were performed, which enabled assignment of the correct structure of. baulamycin A. Key features of the convergent and fully stereocontrolled route include Evans Aldol and Brown allylation reactions to construct the left fragment, a prolinol amide-derived alkylation/desymmetrization to install the methyl-substituted centers in the right fragment, and finally, a Carreira alkynylation to join both fragments. In addition, we have determined the inhibitory activities of novel baulamycin A derivatives against the enzyme SbnE. This SAR study provides useful insight into the design of novel SbnE inhibitors that overcome the drug resistance of pathogens, which cause life-threatening infections.
Interested yet? Keep reading other articles of 2419-56-9, you can contact me at any time and look forward to more communication. Application In Synthesis of H-Glu(OtBu)-OH.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics