Chemistry, like all the natural sciences, begins with the direct observation of nature— in this case, of matter.6306-52-1, Name is H-Val-OMe.HCl, SMILES is N[C@@H](C(C)C)C(OC)=O.[H]Cl, belongs to amides-buliding-blocks compound. In a document, author is Glachet, Thomas, introduce the new discover, Recommanded Product: H-Val-OMe.HCl.
Three-component reactions of nitroalkanes, acrylamides, and aldehydes by using a catalytic amount of KOH in DMSO gave beta ‘-hydroxy-gamma-nitro amides. Mechanistic studies suggested that the reactions proceeded by domino Michael/aldol reactions. The highly nucleophilic nature of transient amide enolates that were formed by Michael addition of nitronate anions to acrylamides in DMSO enabled the realization of catalytic intermolecular aldol reactions of amide enolates in the presence of acidic nitroalkanes.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 6306-52-1. Recommanded Product: H-Val-OMe.HCl.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics