In an article, author is Gray, Amber L. H., once mentioned the application of 1148-11-4, Name is Z-Pro-OH, molecular formula is C13H15NO4, molecular weight is 249.26, MDL number is MFCD00003170, category is amides-buliding-blocks. Now introduce a scientific discovery about this category, Recommanded Product: 1148-11-4.
A novel and efficient method for the nucleophilic alpha-hydrolysis of alpha-halohydroxamates with water under metal-free conditions is described. In this reaction, the simple and readily available dimethyl sulfoxide (DMSO) was used as a catalyst, while water served as the nucleophile and oxygen source. This method was successfully employed in the synthesis of secondary alpha-hydroxy-alpha-alkyl and alpha-hydroxy-alpha-arylhydroxamates as well as tertiary alpha-hydroxy-alpha-dialkylhydroxamates. Furthermore, the alpha-hydrolysis of alpha-halo-alpha-dialkylhydroxamates was achieved in the absence of the DMSO catalyst. This is a novel, mild, less toxic, and facile strategy for alpha-hydroxylation of amides.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 1148-11-4, Recommanded Product: 1148-11-4.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics