A common compound: 6292-59-7, name is 4-(tert-Butyl)benzenesulfonamide, belongs to amides-buliding-blocks compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below. 6292-59-7
General procedure: The N-R-sulfonyldithiocarbimate potassium salts were prepared in dimethylformamide (DMF) from the sulfonamides in reaction with carbon disulfide and potassium hydroxide analogously as described in the literature [9,22,23]. Carbon disulfide (10mmol) and potassium hydroxide (20mmol) were added to a solution of the corresponding sulfonamide (10mmol) in DMF (25mL). The mixture was stirred for approximately 4h up to the total consumption of KOH. Upon the addition of 20mL of ice cold ethanol, a yellowish solid is formed. The product was separated by filtration, washed with ice ethanol, ethyl acetate, diethyl ether, and dried under reduced pressure (yields 70-85%, based on the sulfonamide). The compounds 1a-e are described in literature [9,22,23]. The data for the new potassium dithiocarbimates 1f-h are as follows.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 6292-59-7, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Vidigal, Antonio E.C.; Rubinger, Mayura M.M.; de Queiroz, Luan F.; da Silva, Lucas F.; Zambolim, Laercio; Guilardi, Silvana; Souza, Rafael A.C.; Ellena, Javier; Wetler, Emiliana B.; Oliveira, Marcelo R.L.; Inorganica Chimica Acta; vol. 486; (2019); p. 724 – 732;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics