Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 683-57-8, Name is 2-Bromoacetamide, molecular formula is C2H4BrNO, belongs to amides-buliding-blocks compound. In a document, author is Osmaniye, Derya, introduce the new discover, Computed Properties of https://www.ambeed.com/products/683-57-8.html.
As an amide fungicide, fenhexamid has been extensively used to control botrytis and sderotinia as well as antagonize the resistant bacteria produced by other pesticides. But because of the accumulation of residues in fruit and vegetable products, it may have an adverse effect on the health of human and animals. In this work, the exploration of the interaction between fenhexamid and calf thymus DNA (ct-DNA) was carried out by fluorescence spectroscopy, IJV-vis spectroscopy, circular dichroism, viscosity measurement, melting measurements, molecular docking and molecular dynamics simulation. The results implied that fenhexamid bound onto ct-DNA in terms of groove binding. And the outcomes from circular dichroism measurements demonstrated a slight change in the ct-DNA helical structure during the binding process. In addition, the combination ratio of fenhexamid with ct-DNA was 1:1 and the association constant was 2.52 x 10(3) M-1 at 298 K. The measured thermodynamic parameters indicated that hydrogen bonding interaction and van der Waals forces become more dominant during interacting fenhexamid with ct-DNA, which was further confirmed through computer simulation technique. (C) 2019 Elsevier B.V. All tights reserved.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 683-57-8. Computed Properties of https://www.ambeed.com/products/683-57-8.html.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics