Application of 86-86-2, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 86-86-2, Name is 1-Naphthaleneacetamide, SMILES is C1=CC=CC2=CC=CC(=C12)CC(N)=O, belongs to amides-buliding-blocks compound. In a article, author is Kolla, Nathan J., introduce new discover of the category.
An unprecedented rhodium(III)-catalyzed hydroarylation of ,-difluoromethylene alkynes with N-pivaloxyl aroylamides through sequential C-H activation and aryl migration is detailed herein. A large array of ,-difluoromethylene alkynes and N-pivaloxyl aryl amides were amenable to this transformation, thus providing a novel synthetic protocol for the construction of difluorinated 2-alkenyl aniline derivatives in high yields and with excellent regioselectivity. Notably, unique fluorine effects were found to underlie the thus unconventional reaction manifold.
Application of 86-86-2, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 86-86-2.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics