Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Safety of H-Glu(OtBu)-OtBu.HCl, 32677-01-3, Name is H-Glu(OtBu)-OtBu.HCl, molecular formula is C13H26ClNO4, belongs to amides-buliding-blocks compound. In a document, author is Li, Yang, introduce the new discover.
T3P mediated intramolecular rearrangement of o-aminobenzamide to o-ureidobenzonitrile using isothiocyanates
Current work describes the environmentally benign approach for the synthesis of o-ureidobenzonitriles, from o-aminobenzamides and isothiocyanates using T3P. Here, the conversion of thiourea to urea and amide to nitrile take place simultaneously via unprecedented intramolecular rearrangement. This protocol is operationally facile and offers wide variety of o-ureidobenzonitriles at room temperature in good to excellent yields.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 32677-01-3. Safety of H-Glu(OtBu)-OtBu.HCl.