Related Products of 6292-59-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 6292-59-7, Name is 4-(tert-Butyl)benzenesulfonamide, SMILES is C1=CC(=CC=C1C(C)(C)C)[S](N)(=O)=O, belongs to amides-buliding-blocks compound. In a article, author is Liu, Haijuan, introduce new discover of the category.
Aza-heterocyclic frameworks through intramolecular pi-system trapping of spiro-N-acyliminiums generated from isoindolinone
Spiro-acetoxylactams as key substrates were obtained straightforwardly by the tandem regioselective reduction/O-acylation of spiro-isoindolinone-imides. The latter were produced in large scale in three steps from homophthalic acid. These imides were useful to provide in one step isoindolinones bearing hydroxymethyl-amide functions, tethered at quaternary carbon centre with promising biological issues. Submitted to Bronsted (TFA neat) and Lewis acid (trimethylsilyltrifluoro-methanesulfonic (TMSOTf) 10 mol%), the spiro-acetoxylactams undergo pi-cyclization of spiro-N-acyliminiums to provide diastereoselectively with pi-aromatic original pyrrolopyrido- and pyrroloazepino-isoindoles fused or not to aromatic systems. With pi-olefins, pyrrolopyridines and pyrrolo-azepines fused to isoindoline or containing amino-acids were isolated. A reaction mechanism producing all these systems is also discussed.
Related Products of 6292-59-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 6292-59-7 is helpful to your research.