Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 2799-16-8, Name is (R)-1-Aminopropan-2-ol, SMILES is C[C@@H](O)CN, belongs to amides-buliding-blocks compound. In a document, author is Zhao, Zefeng, introduce the new discover, Application In Synthesis of (R)-1-Aminopropan-2-ol.
Oxaziridine cleavage with a low-valent nickel complex: competing C-O and C-N fragmentation from oxazanickela(II)cyclobutanes
Reacting the low-valent nickel complex [(dtbpe)Ni](2)(mu-eta(2): eta(2)-C6H6) with oxaziridines was found to form mixtures of imine, amide and aldehyde products. If the N-substituent of the oxaziridine is sufficiently bulky, a short-lived intermediate can be isolated and characterized by X-ray diffraction studies as an oxazanickela(II) cyclobutane. This is the first well-defined example of N-O oxidative addition of an oxaziridine to a transition metal. Subsequent fragmentation of this oxazanickelacyclobutane forms a complex mixture of products, including a nickel(II) imido complex, demonstrating that oxaziridines can serve as nitrene precursors. Preliminary mechanistic analysis is consistent with a bimetallic mechanism of fragmentation of the oxazanickelacyclobutane to form the nickel imido and eta(2)-aldehyde complexes.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2799-16-8 is helpful to your research. Application In Synthesis of (R)-1-Aminopropan-2-ol.