52-52-8, Name is 1-Aminocyclopentanecarboxylic acid, molecular formula is C6H11NO2, belongs to amides-buliding-blocks compound, is a common compound. In a patnet, author is Olalere, Olusegun Abayomi, once mentioned the new application about 52-52-8, Computed Properties of C6H11NO2.
Increase in furfural tolerance by combinatorial overexpression of NAD salvage pathway enzymes in engineered isobutanol-producing E. coli
To reduce the furfural toxicity for biochemical production in E. coli, a new strategy was successfully applied by supplying NAD(P) H through the nicotine amide salvage pathway. To alleviate the toxicity, nicotinamide salvage pathway genes were overexpressed in recombinant, isobutanol-producing E. coli. Gene expression of pncB and nadE respectively showed increased tolerance to furfural among these pathways. The combined expression of pncB and nadE was the most effective in increasing the tolerance of the cells to toxic aldehydes. By comparing noxE-and fdh-harbouring strains, the form of NADH, rather than NADH, was the major effector of furfural tolerance. Overall, this study is the application of the salvage pathway to isobutanol production in the presence of furfural, and this system seems to be applicable to alleviate furfural toxicity in the production of other biochemical. (C) 2017 Elsevier Ltd. All rights reserved.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 52-52-8. The above is the message from the blog manager. Computed Properties of C6H11NO2.