4943-86-6, name is 2-Amino-N-(4-chlorophenyl)benzamide, belongs to amides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C13H11ClN2O
General procedure: A mixture of 4-methoxybenzyl alcohol (0.138 g, 1 mmol), I2 (0.254 g, 1 mmol), K2CO3(0.138 g, 1 mmol), isatoic anhydride (0.163 g, 1 mmol) and aniline (0.093 g,1 mmol) in water (5 mL) was stirred for 3 h at reflux. After reaction completion,the mixture was cooled to room temperature and stirred for 1 h. The resultingprecipitate was filtered, washed with water (3 3 mL), and purified by recrystallization from ethanol to give 4a as a white solid.
The synthetic route of 4943-86-6 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Azimi, Seyedeh Bahareh; Azizian, Javad; Tetrahedron Letters; vol. 57; 2; (2016); p. 181 – 184;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics