Novel and efficient one-pot tandem synthesis of tryptanthrin derivatives for biological activity was written by Rama Krishnam Raju, Addada;Venkata Reddy, Regalla;Venkateswara Rao, Anna. And the article was included in International Journal of Pharma Research and Health Sciences in 2018.Related Products of 54166-95-9 This article mentions the following:
The derivatives of tryptanthrins I [R = H, 1-Me, 2-Br, etc; R1 = H, 8-OMe, 8-Br, etc.] were prepared from three schemes. Those tryptanthrin derivatives I were characterized by NMR study. Treatment of an equimolar mixture of anthranilamides and 2-bromoacetophenones afforded indolo[2,1-b]-quinazoline-6,12-diones (tryptanthrin). In the experiment, the researchers used many compounds, for example, 6-Chloro-2-aminobenzamide (cas: 54166-95-9Related Products of 54166-95-9).
6-Chloro-2-aminobenzamide (cas: 54166-95-9) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Related Products of 54166-95-9
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics