Deep Eutectic Solvent Mediated Carbonylation of Amines and Alcohols by Using Dimethyl Carbonate: Selective Symmetrical Urea and Organic Carbonate Synthesis was written by Karimi, Farzaneh;Shariatipour, Monire;Heydari, Akbar. And the article was included in ChemistrySelect in 2021.HPLC of Formula: 2387-23-7 This article mentions the following:
This work presented one-pot synthesis of sym. organic carbonates and ureas by employing cheap and biodegradable deep eutectic solvent as the catalyst and reaction media. The effect of different reaction parameters such as temperature, DMC/amines and alcs. ratio and reaction time were investigated on the reaction efficiency. This new protocol provided a simple, fast, and sustainable approach and proceeded with high efficiency with aliphatic and aromatic amines and alcs. as well. Finally, applicability of this methodol. was also examined for reaction of nucleophiles such as Ph hydrazine and Ph glycine with di-Me carbonate. Interestingly, it was found that this reaction system obtained good yields of product for both of them. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7HPLC of Formula: 2387-23-7).
1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.HPLC of Formula: 2387-23-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics