Sandbrink, Jessica published the artcileSolid Support Post-Conjugation of Amino Acids and a Phenanthroline Derivative to a Central Position in Peptide Nucleic Acids, Formula: C40H35N7O8, the publication is Nucleosides, Nucleotides & Nucleic Acids (2007), 26(10-12), 1485-1489, database is CAplus and MEDLINE.
A solid-phase synthesis strategy for post-conjugation of amino acids and a phenanthroline derivative to peptide nucleic acids is described. The peptide nucleic acids, synthesized by 9-fluorenylmethyloxycarbonyl chem. on TentaGel S Rink Amide resin, have an internally placed unit carrying an amino linker with 4-methyltrityl protection. Methyltrityl removal by mild acidic conditions and conjugation of amino acids or a phenanthroline derivative, via an amide or urea linker, was performed on-resin after completion of the chain assembly. This solid phase methodol. resulted in excellent purities of the crude conjugates.
Nucleosides, Nucleotides & Nucleic Acids published new progress about 186046-83-3. 186046-83-3 belongs to amides-buliding-blocks, auxiliary class Purine,Carboxylic acid,Amine,Benzene,Amide,Others,PNA,, name is 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2-(((benzhydryloxy)carbonyl)amino)-6-oxo-5H-purin-9(6H)-yl)acetamido)acetic acid, and the molecular formula is C40H35N7O8, Formula: C40H35N7O8.
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https://en.wikipedia.org/wiki/Amide,
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