Lygina, Antonina S. published the artcileTransmembrane Domain Peptide/Peptide Nucleic Acid Hybrid as a Model of a SNARE Protein in Vesicle Fusion, Name: 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2-(((benzhydryloxy)carbonyl)amino)-6-oxo-5H-purin-9(6H)-yl)acetamido)acetic acid, the publication is Angewandte Chemie, International Edition (2011), 50(37), 8597-8601, S8597/1-S8597/15, database is CAplus and MEDLINE.
A novel simplified model was introduced for membrane fusion mediated by SNARE proteins. The SNARE mimetic system consisted of hybrids between the transmembrane domain/linker segments from natural membrane-bound SNARE proteins and peptide nucleic acid recognition motifs. Owing to the complementarity of the PNA bas pairs, it was possible to investigate the fusion complexes with both helixes linked on the same and opposite sides of the recognition motif. The new PNA/peptide hybrids facilitated fusion of vesicles dependent on the PNA base pair sequence and on temperature
Angewandte Chemie, International Edition published new progress about 186046-83-3. 186046-83-3 belongs to amides-buliding-blocks, auxiliary class Purine,Carboxylic acid,Amine,Benzene,Amide,Others,PNA,, name is 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2-(((benzhydryloxy)carbonyl)amino)-6-oxo-5H-purin-9(6H)-yl)acetamido)acetic acid, and the molecular formula is C40H35N7O8, Name: 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2-(((benzhydryloxy)carbonyl)amino)-6-oxo-5H-purin-9(6H)-yl)acetamido)acetic acid.
Referemce:
https://en.wikipedia.org/wiki/Amide,
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