Hoerlein, Ulrich published the artcileNonsymmetric N-substituted bispidine (3,7-diazabicyclo[3.3.1]nonane. I, Formula: C5H8N2O, the publication is European Journal of Medicinal Chemistry (1977), 12(4), 301-5, database is CAplus.
Bispidine derivatives I [R = R1 = Me, RR1 = (CH2)5, R2 = Me, Et, CH2Ph, R3 = H; RR1 = (CH2)4, R2 = Me, Et, R3 = H] were prepared by condensing RR1C:C(CN)CO2Et with R2NHCOCH2CN, hydrolyzing II, and reducing diimides with LiAlH4. I [R3 = acyl, 4-FC6H4CO(CH2)3, 8-chloro-10,11-dihydrobenzo[b,f]thiepin-10-yl] were prepared by substitution of I (R3 = H). I [RR1 = (CH2)5, (CH2)4, R2 = Me, R3 = COCH2Ph] had analgesic activities of the same magnitude as morphine. Some other I exhibited various pharmacol. activity, but only to a degree.
European Journal of Medicinal Chemistry published new progress about 15029-36-4. 15029-36-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Aliphatic hydrocarbon chain,Amide, name is 2-Cyano-N-ethylacetamide, and the molecular formula is C5H8N2O, Formula: C5H8N2O.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics