Zhang, Jinqi’s team published research in Nanjing Daxue Xuebao, Ziran Kexue in 32 | CAS: 530-40-5

Nanjing Daxue Xuebao, Ziran Kexue published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H11NO4, Safety of N,N-Diethylisonicotinamide.

Zhang, Jinqi published the artcileStudy on the aluminum amides conversion of esters to amides, Safety of N,N-Diethylisonicotinamide, the publication is Nanjing Daxue Xuebao, Ziran Kexue (1996), 32(2), 242-245, database is CAplus.

A convenient method was used for directly converting esters to amides by using the reagents derived from the reaction of trimethylaluminum with ammonium chloride, primary amines hydrochloride or secondary amines hydrochloride at high yield in relatively short reaction time and at low temperature Reactions of aluminum amides with aromatic esters were extensively studied and the influence of different substituting groups on the reaction was discussed. It was concluded that, if an electron-donating group was attached to the nitrogen atom instead of hydrogen, the reactivity of the aluminum amide would be increased, and, if an electron-withdrawing group was attached to benzene ring, the electron-deficiency of carboyl carbon would be increased, the yield of amides would be also increased.

Nanjing Daxue Xuebao, Ziran Kexue published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H11NO4, Safety of N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics