Watanabe, M. published the artcileTandem directed metalation reactions. Short syntheses of polycyclic aromatic hydrocarbons and ellipticine alkaloids, COA of Formula: C10H14N2O, the publication is Journal of the American Chemical Society (1980), 102(4), 1457-60, database is CAplus.
Starting with N,N-diethylbenzamides and aromatic aldehydes and proceeding via ortho lithiated intermediates, a one-pot synthesis of anthraquinones, e.g. I and II, was achieved. The scope and limitations of this tandem metalation sequence was explored for a variety of aromatic and heteroaromatic amides and aldehydes. The use of this reaction for the short syntheses of carcinogenic polycyclic aromatic hydrocarbons and antitumor ellipticine alkaloids, e.g. III was demonstrated.
Journal of the American Chemical Society published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C12H25Br, COA of Formula: C10H14N2O.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics