Xie, Jianwei published the artcileTransition-metal-free decarboxylative amidation of aryl α-keto acids with diphenylphosphoryl azide: new avenue for the preparation of primary aryl amides, Recommanded Product: 2,4-Dichlorobenzamide, the publication is Youji Huaxue (2020), 40(12), 4284-4289, database is CAplus.
In this paper, a novel transition-metal-free decarboxylative amidation of (heteroaryl)aryl α-keto acids ArC(O)C(O)OH (Ar = 2,4-dichlorophenyl, naphthalen-2-yl, thiophen-2-yl, etc.) with diphenylphosphoryl azide (DPPA) under mild conditions has been developed. The reaction proceeded smoothly to afford the corresponding primary (heteroaryl)aryl amide products ArC(O)NH2 in good to excellent yields under air and showed excellent functional group tolerance. Gram-scale reaction was also performed to produce the desired product in high yield. In addition, the mechanism of the present reaction was investigated.
Youji Huaxue published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C12H10O4S, Recommanded Product: 2,4-Dichlorobenzamide.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics