Karpun, Yevhen published the artcileThe investigation of antimicrobial activity of some s-substituted bis-1,2,4-triazole-3-thiones, Computed Properties of 79-07-2, the publication is Pharmacia (Sofia, Bulgaria) (2021), 68(4), 797-804, database is CAplus.
New S-substituted 4-alkyl-(5-((3-(pyridin-4-yl)-1H-1,2,4-triazole-5-yl)thio)methyl)-4H-1,2,4-triazole-3-thiol derivatives have been designed, synthesized and studied their antimicrobial activity on 11 standard Gram-pos. and Gram-neg. microorganism strains. Their spectral and physicochem. parameters were established using modern comprehensive methods of anal., including 1H NMR spectroscopy, GC-MS and elemental anal.It has been found that compound 2a exhibits strong suppression of 5 test strains (MBC = 15.6 μg/mL). Compound 4a showed moderate inhibition of Salmonella pullorum, Escherichia coli O2 , Salmonella enteritidis strains (MBC = 31.25 μg/mL) Compound 6a was sensitive toward ten tested bacteria at 31.25μg/mL concentration
Pharmacia (Sofia, Bulgaria) published new progress about 79-07-2. 79-07-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Aliphatic hydrocarbon chain,Amide,Inhibitor, name is 2-Chloroacetamide, and the molecular formula is C2H4ClNO, Computed Properties of 79-07-2.
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