Zaitseva, N.A.’s team published research in Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya in | CAS: 360-92-9

Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C4Br2N2O4S, Product Details of C6H10F3NO.

Zaitseva, N.A. published the artcileSynthesis of fluorinated ketones with organolithium compounds and N,N-dialkylamides of fluorinated acids, Product Details of C6H10F3NO, the publication is Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya (1961), 831-5, database is CAplus.

cf. CA 53, 17933g. Adding 17.2 g. CHF2CONEt2 (I) in Et2O to PhLi (0.1 mole PhBr) in Et2O at -70° and stirring 2 hrs. gave after treatment with dilute HCl 83% CHF2Bz, b10-12 63-5°, n20D 1.4900. Similar reaction with crystalline PhLi in MePh gave a 67% yield, while the use of PhNa in MePh gave but 29% product. 2-Thienyllithium and I gave 75% 2-CHF2-COC4H3S, b11 77-80°, b13 80°. Similarly, PhLi and CF3CONEt2 (II) gave 74% CF3Bz, b37 66-8°, 1.4578, in Et2O, while the yield was 54.5% in MePh. 2-Thienyllithium and II in Et2O gave 39% 2-CF3COC4H3S, b23-4 67°. CF3COCl and Et2NH in Et2O at 0° gave 47.4% II, b43 74-5°. PhLi in Et2O and CHFClCONEt2 gave 53% CHFClBz, b11 91°. Addition of 40.8 g. I to 0.36 mole BuLi in Et2O over 2 hrs. at room temperature gave 32.6% CHF2COBu, b. 111-12°.

Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C4Br2N2O4S, Product Details of C6H10F3NO.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics