Simonov, A. Yu. published the artcileOptimization of the Synthesis of New Antibacterial Compounds with Tris(1-Alkylindol-3-yl)Methylium Fragments, Synthetic Route of 79-07-2, the publication is Pharmaceutical Chemistry Journal (2021), 54(12), 1263-1268, database is CAplus.
A new optimal synthetic scheme for new antibacterial compounds I (R = H, Me) combining tris-(1-alkyindol-3-yl)methylium and 3-(indol-1-yl)maleimide in their structures was developed. The proposed method provided a significant increase in the product yield, reduced the labor intensiveness and number of steps, and used readily accessible starting reagents. A good yield was achieved for 3-(formylindol-1-yl)-4-chloromaleimide, a universal precursor enabling two-step syntheses of target tri(indolyl)methanes II (R1 = H, NH2, NMe2) and production of an extensive library of analogous potentially active compounds from other 1-alkylindoles and various amines and thiols.
Pharmaceutical Chemistry Journal published new progress about 79-07-2. 79-07-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Aliphatic hydrocarbon chain,Amide,Inhibitor, name is 2-Chloroacetamide, and the molecular formula is C13H21BN2O2, Synthetic Route of 79-07-2.
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https://en.wikipedia.org/wiki/Amide,
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