Lee, Wongyu published the artcilePhotoinduced α-C-H Amination of Cyclic Amine Scaffolds Enabled by Polar-Radical Relay, SDS of cas: 169590-42-5, the publication is Angewandte Chemie, International Edition (2022), 61(25), e202202971, database is CAplus and MEDLINE.
Herein, a polar-radical relay strategy for α-C-H amination of cyclic amines with N-chloro-N-sodio-carbamates is reported. The relay is initiated by in situ generation of a cyclic iminium intermediate using N-iodosuccinimide oxidant as an initiator, which then operates through a series of polar (addition and elimination) and radical (homolysis, hydrogen- and halogen atom transfer) reactions to enable the challenging C-N bond formation in a controlled manner. A broad range of α-amino cyclic amines were readily accessed with excellent regioselectivity, and the superb applicability was further demonstrated by functionalization of biol. relevant compounds
Angewandte Chemie, International Edition published new progress about 169590-42-5. 169590-42-5 belongs to amides-buliding-blocks, auxiliary class Sulfamide,Immunology/Inflammation,COX, name is 4-(5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide, and the molecular formula is C17H14F3N3O2S, SDS of cas: 169590-42-5.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics