Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis was written by Hwang, Jong Yeon;Smithson, David;Connelly, Michele;Maier, Julie;Zhu, Fangyi;Guy, Kiplin R.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2010.SDS of cas: 83909-69-7 The following contents are mentioned in the article:
A series of halo-nitrobenzamides were synthesized and evaluated for their ability to block proliferation of Trypanosoma brucei brucei. A number of these compounds had significant activity against the parasite, particularly 2-chloro-N-(4-chlorophenyl)-5-nitrobenzamide which exhibited low micromolar inhibitory potency against T. brucei and selectivity towards both malaria and mammalian cells. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7SDS of cas: 83909-69-7).
N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.SDS of cas: 83909-69-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics