Chavan, Sunil S. published the artcileIonic liquid-catalyzed 4,6-disubstituted-3-cyano-2-pyridone synthesis under solvent-free conditions, Safety of 2-Cyano-N-ethylacetamide, the publication is Catalysis Letters (2011), 141(11), 1693-1697, database is CAplus.
A green protocol for the synthesis of 4,6-disubstituted-3-cyano-2-pyridones from cyanoacetamides and 1,3-dicarbonyl compounds or chalcones using guanidine-based ionic liquid as catalyst was developed. In solvent-free conditions at 30 °, 1,1,3,3-tetramethylguanidine lactate had the highest catalytic activity among the ionic liquids including 1,1,3,3-tetramethylguanidine acetate, 1,1,3,3-tetramethylguanidine propionate, 1,1,3,3-tetramethylguanidine n-butyrate, and 1,1,3,3-tetramethylguanidine trifluoroacetate. The catalyst was recovered and recycled several times without significant loss of catalytic activity.
Catalysis Letters published new progress about 15029-36-4. 15029-36-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Aliphatic hydrocarbon chain,Amide, name is 2-Cyano-N-ethylacetamide, and the molecular formula is C5H8N2O, Safety of 2-Cyano-N-ethylacetamide.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics