Kheradmand, Farrah published the artcileLeukotriene A4 hydrolase: the janus enzyme shows its ugly side in smokers, Synthetic Route of 321673-30-7, the publication is American Journal of Respiratory and Critical Care Medicine (2014), 190(1), 5-7, database is CAplus and MEDLINE.
This paper describes the cigarette smoke chem. acetylates proline-glycine-proline, enhancing its chemotactic activity and protecting it from degradation by LTA4H. And also biochem. and preliminary murine studies suggest that cigarette smoke can selectively abrogate the peptidase activity of LTA4H, with minimal effect on the hydrolase activity.
American Journal of Respiratory and Critical Care Medicine published new progress about 321673-30-7. 321673-30-7 belongs to amides-buliding-blocks, auxiliary class Immunology/Inflammation,Scavenger receptor, name is [(2-Hexylcyclopentylidene)amino]thiourea, and the molecular formula is C12H23N3S, Synthetic Route of 321673-30-7.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics