Woronick, Charles L. published the artcileSpectrophotofluorometric determination of the dissociation constants of amides from the enzyme-reduced coenzyme complex of liver alcohol dehydrogenase(ADH), Product Details of C2H3F2NO, the main research area is .
cf. ibid. 15(10), 2062(1961). A mixture of ADH and reduced diphosphopyridine nucleotide (DPNH) in solution, which contains a fluorescent ADH-DPNH complex, was titrated with solutions of amides while the fluorescence at 410 mμ was measured. Dissociation constants were obtained by plotting the reciprocal of the change in fluorescence intensity vs. the reciprocal of the amide concentration (method of Winer and Theorell, CA 56, 9102g). Values of KER.I. are tabulated for 17 amides (E = enzyme, R = DPNH, I = inhibitor (amide)). These agree well with the Michaelis constants obtained previously. The values are also plotted according to the Taft ρ*σ* equation and the correlations are discussed.
Acta Chemica Scandinavica published new progress about Dissociation. 359-38-6 belongs to class amides-buliding-blocks, name is 2,2-Difluoroacetamide, and the molecular formula is C2H3F2NO, Product Details of C2H3F2NO.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics