Venkatramaiah, T. published the artcileDesign, synthesis and evaluation of chlorothiazide derivatives, Recommanded Product: N-Methylformamide, the main research area is chlorothiazide preparation antibacterial antifungal.
Hydrochlorothiazide and chlorthiazide are high potent diuretics used in treatment of hypertension. In recent research trends shows that chlorthiazide derivatives are used in osteoporosis and also has antimicrobial activity against various bacterial species. In this view a series of chlorthiazide derivatives were designed, synthesized six compounds by condensing chloroacetyl chloride with chlorthiazide by using ethanol as a solvent refluxed at 60° temperature Formed compound is taken as intermediate and further refluxed and condensed with aromatic amines to give substituted chlorthiazide derivatives The substituted chlorthiazide derivatives were screened for antibacterial activity.
Asian Journal of Pharmaceutical Analysis and Medicinal Chemistry published new progress about Antibacterial agents. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics