Swetha, Sathyendran published the artcileAn Umpolung Route to Amides from α-Aminonitriles under Metal-Free Conditions, Related Products of amides-buliding-blocks, the main research area is secondary tertiary amide preparation umpolung; aminonitrile decyanation.
A metal-free, base-mediated decyanation of α-aminonitriles has been developed to synthesize secondary and tertiary amides using O2 or air as an amide oxygen source. Radical scavenging studies disclosed that the cleavage of C-CN bond may proceed via an anionic pathway. The practicality of the work was also demonstrated through an in situ generated α-aminonitriles from corresponding aldehydes and amines to afford amides. The important features of this work include broad functional group compatibility, 41% to 89% product yields, gram-scale synthesis of 2° and 3° amides, broad substrate scope, and an umpolung strategy.
Advanced Synthesis & Catalysis published new progress about Amides, secondary Role: SPN (Synthetic Preparation), PREP (Preparation). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Related Products of amides-buliding-blocks.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics