On November 15, 2013, Karmase, Aniket; Jagtap, Sneha; Bhutani, Kamlesh K published an article.Category: amides-buliding-blocks The title of the article was Anti adipogenic activity of Aegle marmelos Correa.. And the article contained the following:
In continuation of evaluating the anti-obesity effect of Aegle marmelos, we have screened the n-hexane, dichloro methane (DCM), ethyl acetate (EtOAc) and methanol (MeOH) extracts of the leaves at the concentration of 25, 50, 75 and 100 μg/ml for adipogenesis inhibition in the adipocytes. Nile red staining with the help of fluorometry was used as indicator of the antiobesity activity. The most active DCM extract showed the 33.98±3.55% lipid content at 100μg/ml and was selected for the further isolation. 14 compounds were isolated from DCM extract of A. marmelos leaves. The compounds were screened for the adipogenesis inhibition at 50 and 100 μM concentrations. Out of the 14 compounds, halfordinol, ethyl ether aegeline and esculetin were showing 10.04±0.52, 16.29±0.85 and 25.09±1.31% lipid content respectively at 100 μM. We hereby report the adipogenesis inhibition by A. marmelos as one of the pathway for its antiobesity effect. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Category: amides-buliding-blocks
The Article related to 3t3-l1 cells, adipogenesis: drug effects, adipose tissue: cytology, adipose tissue: drug effects, adipose tissue: metabolism, aegle: chemistry, amides: isolation & purification, amides: pharmacology, animals, anti-obesity agents: pharmacology, lipid metabolism: drug effects, mice, obesity: prevention & control and other aspects.Category: amides-buliding-blocks
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics