Cornwell, E. et al. published their research in Anales de la Real Academia Nacional de Farmacia in 2007 |CAS: 97-09-6

The Article related to qspr benzene sulfonamide derivative, General Organic Chemistry: Other and other aspects.Application of 97-09-6

Cornwell, E. published an article in 2007, the title of the article was Application of the Vc3 topographic QSPR parameter to benzene sulfonamide derivatives.Application of 97-09-6 And the article contains the following content:

A novel QSPR topog. parameter (Vc3) is used for reduction of the number of independent variables to one variable Vc3, consistent with Euclidian distances relations. This procedure was applied to a model of 19 benzene sulfonamide derivatives, using benzenesulfonamide as a reference The derivatives were characterized by physicochems. properties used as independent variables. The variables are: refraction index, surface tension and an extra dummy variable that indicated the presence or absence chlorine atoms in the mol., while pKa was used like dependent variable. The linear regression proposed is of the form. pKa = m* Vc3 + n, that is more coherent than its counterpart multivariable regression. The use of this variable reduction eliminated problems of orthogonal procedure or the use of Principal Component Anal. (PCA) to obtain consistent models. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Application of 97-09-6

The Article related to qspr benzene sulfonamide derivative, General Organic Chemistry: Other and other aspects.Application of 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics