On November 15, 2004, Jaiswal, Mona; Khadikar, Padmakar V.; Supuran, Claudiu T. published an article.COA of Formula: C6H5ClN2O4S The title of the article was Topological modeling of lipophilicity, diuretic activity, and carbonic inhibition activity of benzene sulfonamides: a molecular connectivity approach. And the article contained the following:
A large series of distance-based topol. indexes has been used for modeling lipophilicity, diuretic activity, and carbonic anhydrase inhibition activity of a library of simple substituted benzene sulfonamides. The results have shown that the topol. approach used is quite useful for modeling carbonic anhydrase inhibition and the use of mol. connectivity is the best for this purpose. Excellent results are obtained in multiparametric regressions. The results are critically discussed on the basis of statistical parameters. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).COA of Formula: C6H5ClN2O4S
The Article related to qsar benzene sulfonamide diuretic carbonic anhydrase, Pharmacology: Structure-Activity and other aspects.COA of Formula: C6H5ClN2O4S
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics