On February 1, 2022, Xu, Xu; Zhao, Wenhao; Ji, Baocheng; Han, Yu; Xu, Gaigai; Jie, Mingsha; Wu, Nan; Wu, Yongmei; Li, Junguang; Li, Ke; Zhao, Dianbo; Bai, Yanhong published an article.COA of Formula: C8H10N2O3S The title of the article was Application of silanized melamine sponges in matrix purification for rapid multi-residue analysis of veterinary drugs in eggs by UPLC-MS/MS. And the article contained the following:
Fast and convenient matrix purification is an important prerequisite for high-throughput anal. of drug multiresidues in food. In this study, a silanized melamine sponge was prepared and first applied in the rapid determination of multiclass veterinary drugs in eggs by ultrahigh-performance liquid chromatog.-tandem mass spectrometry. Within five seconds, fast, convenient and efficient matrix separation could be achieved through simple soaking and squeezing. Compared to other matrix adsorbents, the developed material demonstrated equivalent or better purification performance. Good validation results were obtained in terms of drug recoveries (61.5%∼97.0%, relative standard deviation (RSD) ≤ 10.8%), and linearities (R2 ≥ 0.999), as well as low limits of quantitation (0.3 ∼ 10.9μg·kg-1) and detection (0.1 ∼ 3.8μg·kg-1). By analyzing 52 egg samples, high concentrations of ofloxacin, trimethoprim, metronidazole, and dimetridazole were found at 542.9, 121.2, 66.1 and 58.0μg·kg-1, resp. The silanized melamine sponge has shown its great potential for rapid anal. of multiclass residues in food safety. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).COA of Formula: C8H10N2O3S
The Article related to silanized melamine sponges matrix purification drug residue uplc ms, egg, mass spectrometry, matrix purification, melamine sponge, veterinary drug, Food and Feed Chemistry: Analysis and other aspects.COA of Formula: C8H10N2O3S
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics