The synthesis of proximal-benzoguanine and a simplified synthesis of proximal-benzohypoxanthine was written by Schneller, Stewart W.;Ibay, Augusto C.. And the article was included in Journal of Organic Chemistry in 1986.Formula: C7H7ClN2O This article mentions the following:
7-Aminoimidazo[4,5-f]quinazolin-9(8H)-one (proximal-benzoguanine I, R = NH2) was prepared in five steps from 2-amino-6-chlorobenzamide. Methylation of I (R = NH2) gave exclusively 7-amino-3-methylimidazo[4,5-f]quinazolin-9(8H)-one(II). (proximal-Benzohypoxanthine I(R = H) was available directly from 3-amino-2,6-dinitrobenzonitrile in a more efficient route than the one previously reported in the literature. In the experiment, the researchers used many compounds, for example, 6-Chloro-2-aminobenzamide (cas: 54166-95-9Formula: C7H7ClN2O).
6-Chloro-2-aminobenzamide (cas: 54166-95-9) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Formula: C7H7ClN2O
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics