Pan, Li et al. published their research in Gaodeng Xuexiao Huaxue Xuebao in 2013 | CAS: 82097-01-6

2-(2-Chloroethoxy)benzenesulfonamide (cas: 82097-01-6) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Category: amides-buliding-blocks

Design, synthesis and herbicidal activity of novel sulfonylureas containing monosubstituted pyrimidine moiety was written by Pan, Li;Liu, Zhuo;Chen, You-wei;Li, Yong-hong;Li, Zheng-ming. And the article was included in Gaodeng Xuexiao Huaxue Xuebao in 2013.Category: amides-buliding-blocks This article mentions the following:

Sulfonylureas, a unique group of herbicides, were extensively applied to controlling a range of weeds in a variety of crops and vegetables. In order to find efficient sulfonylurea herbicides, the title compounds were designed by introducing monosubstituted pyrimidinamines into some well-known sulfonylurea skeletons. A series of sulfonylurea compounds were synthesized and characterized by 1H NMR and HRMS. Herbicidal activities and IC50 values of the title compounds were determined by Pot plant test and Petri dish test against Brassica napus, Amaranthus retroflexus, Echinochloa crusgalli and Digitaria adscendens. Some compounds exhibited herbicidal activities. Compounds I and II possessed significant inhibition effects against Brassica napus and Amaranthus retroflexus. Further structural modification of novel sulfonylureas containing monosubstituted pyrimidine moiety will be required for improving efficacy against weeds in our laboratory In the experiment, the researchers used many compounds, for example, 2-(2-Chloroethoxy)benzenesulfonamide (cas: 82097-01-6Category: amides-buliding-blocks).

2-(2-Chloroethoxy)benzenesulfonamide (cas: 82097-01-6) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics