Ohrui, Satoshi et al. published their research in Bunseki Kagaku in 1991 | CAS: 5339-69-5

N-Isopropylbenzenesulfonamide (cas: 5339-69-5) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Name: N-Isopropylbenzenesulfonamide

Determination of primary amines by benzenesulfonylation/GC with flame photometric detection was written by Ohrui, Satoshi;Kataoka, Hiroyuki;Miyamoto, Yoshiaki;Ohtsuka, Kimiyo Takeda;Nakita, Masami. And the article was included in Bunseki Kagaku in 1991.Name: N-Isopropylbenzenesulfonamide This article mentions the following:

A selective and sensitive GC (gas chromatog.) method is described for the determination of primary amines. After benzenesulfonylation of by the Hinsberg reaction, primary amines were completely separated from secondary amines by extraction with hexane in 50% KOH-22.5% MeOH solution Benzenesulfonyl derivatives of primary amines in acidic aqueous layer were extracted by Et2O and determined by GC with flame photometric detection (FPD-GC) using a DB-1 capillary column. The FPD-GC calibration curves of amines were linear in the range of 20-1000 ng for the derivatives and the detection limits were about 10-100 pg as injection amounts This was >20 times more sensitive than the results obtained by GC with flame ionization detection. In the experiment, the researchers used many compounds, for example, N-Isopropylbenzenesulfonamide (cas: 5339-69-5Name: N-Isopropylbenzenesulfonamide).

N-Isopropylbenzenesulfonamide (cas: 5339-69-5) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Name: N-Isopropylbenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics